BDBM50043724 (S)-2-({(4R,7S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-14,14-dimethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carbonyl}-amino)-3-phenyl-propionic acid::CHEMBL339320

SMILES CC1(C)SSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key InChIKey=SNEMTHOGAFLXTE-OLAIZJASSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50043724   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50043724((S)-2-({(4R,7S)-13-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  280nMAssay Description:Binding affinity towards mu opioid receptor was determined in rat brain using [3H]CTOP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50043724((S)-2-({(4R,7S)-13-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  83nMAssay Description:Inhibitory concentration against electrically evoked contractions of guinea pig ileum longitudinal muscle-myenteric plexusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50043724((S)-2-({(4R,7S)-13-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  280nMAssay Description:Inhibition of binding of radioligand [3H]CTOP to Opioid receptor mu 1 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50043724((S)-2-({(4R,7S)-13-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  83nMAssay Description:Inhibitory potency against Opioid receptor mu 1 was determined in electrically induced strips of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed